Ivermectin
Appearance: White or yellowish-white
Crystalline powder,
Assay: B1a: 90.0% min(HPLC, Basis,
On drying): (B1a+B1b): 95.0%~100.5%,
Identification: IR and HPLC spectrum,
Concede with standard,
Appearance of solution: Clear and
Not more intensely colored than RS BY7,
Specific optical rotation: -17~ -20 degree,
Relative material: Majors: 2.5% max,
Others: 1% max,
Total impurity: 5.0% max,
Ethanol and formamide: Ethanol: 5.0% max,
Formamide: 3.0% max,
Residue on ignition: 0.1% max,
Heavy metal: 0.002% max,
Water: 1.0% max,