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Zhejiang Chem-Tech Group Co., Ltd.

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10-deacetyl Baccatin ( 10-DAB III )

Product Group: Others

Product Description
As an intermediate for pacilitaxel

Appearance White to off white crystalline powder
Identification
1. FT-IR confirm
2. HPLC confirm
3. NMR confirm
4. Mass confirm
Melting Point 227 ¡ª230 degree
Specific Rotation: -40.0 to -45.0 degree
Lost on Drying NMT 3.0%
Residual Solvent (GC)
Total residual solvents: NMT 1.5%
Methanol: NMT 0.05%
Acetone: NMT 1%
Single largest impurity (except for the following): NMT 0.2%
10-Deacetyl-19-hydroxybaccatin III: NMT 1%
10-deacetyl-2-debenzoyl-2-tigloybaccatin III: NMT 1.0%
10-Deacetyl paclitaxel: NMT 1.0%(HPLC: 16.447s)
10-Deacetyl paclitaxel ethyl analog: NMT 0.3%
10-Deacetyl paclitaxel propyl analog: NMT 0.4%
10-Deacetyl paclitaxel cephalomannine: NMT 0.5%
Assay (HPLC) NLT 99.0%

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