0.625mg/puff.
The Isosorbide Dinitrate is a kind of colourless transparent liquid and kept in a pressuried canister with a metered valve system.

Action And Properties
It is proved by the pharmacological and clinical experiments that Isosorbide Dinitrate exerts a strong effect on the expansion of peripheral blood vessels and reduction of the decrease of oxygen requirement. Meanwhile Isosorbide Dinitrate can also promote the collatteral circulation of the coronary artery, improve the blood supply to the myocardium and protect the endangium etc.

This medicine is apt to be absorbed thoroughly by the mucous membrane of mouth which there is no the first-pass effect, It is rapid in effectiveness within 2-3 minutes, may remain for 90 minutes, reliable in treatment and cause little individual differences. The bioavailability is a hundred percent.

Indications
For the prevention and treatment of various coronary heart diseases and angina pectoris. Especially for the relaxation of the onset of the moderate and severe angina pectoris. When there appear the inducing factors such as mental stress and overfattigue a preventive effect can be obtained by using the Spray in advance.