It prepared from recombinant yeast cultures, is free of association with human blood or blood products. So no risk of disease is induced from contaminated blood.
It has potent protective efficacy. The high seroconversion rates and the high antibody titers n vaccines has been proven.
It is interchangeable with other hepatitis B vaccines. In the clinical studies, no differences were detected in the spectra of antibodies induced in man to yeast-derived or to plasma-derived hepatitis B vaccine. Recombinant Hepatitis B Vaccine (yeast) is used to prevent hepatitis B.
The vaccine has been shown to be as safe and effective as the plasma-derived vaccine, but it is free of association with human blood or blood products. So it's more acceptable.
Vaccination objects: Vaccination with it is recommended in persons of all ages, including infants, children and adults who are or will be at increased risk of infection with hepatitis B virus because of profession. But vaccination should be primarily targeted to infants and children. The one who is to be vaccinated must be free of hepatitis B infection and whose HBsAg must be negative and the aminotransierase level must be normal.